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CBD for Dogs With Anxiety: What the Research Says and 7 Products Compared
A cautious comparison of 7 CBD products for dogs: what each brand claims, what studies actually tested, and where the evidence stops.

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Searching for the best CBD for dogs with anxiety usually leads to bold promises. This guide takes a more careful route. It compares seven CBD products for dogs by what you can check yourself, such as formats, ingredients and testing documents, by what each brand says about its own product, by what published studies actually tested, and by what is still unknown.
Here is the short version. No CBD product is approved by the FDA for dogs. Research on CBD and canine stress is small and mixed, and a result from one product cannot be assumed for another. If your dog’s anxiety affects daily life, start with a veterinary visit. Anxiety in dogs can have medical causes, and your vet can discuss established options such as behavior modification and, where appropriate, prescription medication. Your vet is also the right person to decide whether CBD makes sense for your dog at all. This guide does not give dosing instructions.

What Is the FDA Status of CBD for Dogs?
The FDA states that it has not approved cannabis for any use in animals. The agency says it cannot confirm that cannabis products marketed for pets are safe or effective, it cautions pet owners against using them, and it recommends talking with a veterinarian about appropriate treatment options. Its page on cannabis regulation also lists signs of a bad reaction to watch for, such as lethargy, heavy drooling, vomiting, agitation, tremors and convulsions.
In its animal health updates, the FDA has also treated CBD products marketed with claims such as reducing stress, anxiety or inflammation in animals as unapproved animal drugs, and it has sent warning letters to companies that sold them with those claims. It has said it has not evaluated such products for effectiveness, proper dosage, drug interactions, side effects or manufacturing, that it has received reports of contaminants such as pesticides and heavy metals in some CBD products, and that relying on unproven claims could lead owners to delay veterinary care.
This has practical consequences. Pet CBD products are not reviewed by the FDA for safety, effectiveness, or product quality the way approved animal drugs are before they are marketed. Statements on brand websites about calming or anxiety have not been evaluated by the FDA, and most brands say so in their own fine print. That makes independent lab results and your vet’s opinion more important, not less. Veterinary views on CBD vary, so ask your own vet what they are comfortable discussing. Rules and guidance can change, so check the FDA’s current pages on cannabis and animal health, linked in the Sources below.
What Have Studies Actually Tested?
Published research on CBD in dogs is limited, and the studies that looked at stress or fear are small. Each one tested a specific product, in a specific situation, with a specific group of dogs. None of them tested CBD in general, and none was designed to show that any product on this page helps dogs with anxiety.
Peer-reviewed studies on stress or fear in dogs
| Study | Dogs | What was tested | What the authors reported | Limits to keep in mind |
|---|---|---|---|---|
| Morris et al., Frontiers in Veterinary Science, 2020 | 16 healthy dogs | CBD-containing treats given over one week, then a fireworks-sound test, compared with a control and with trazodone | No effect of CBD on inactivity. The authors wrote that the results did not support an anxiety-reducing effect at the amount used | One product, one amount, one short noise test. Adding CBD weakened a cortisol-lowering effect seen with trazodone |
| Hunt et al., Frontiers in Veterinary Science, 2023 | 40 healthy dogs split between a separation test and a car-ride test | A single dose of a THC-free CBD extract versus placebo before a short separation or car ride | Effects varied by measure and by test. Some stress ratings and, in the car test, cortisol levels were lower than with placebo | Single dose, healthy dogs, small groups, one extract. The authors call for more work on other amounts and formulations |
| Flint et al., Frontiers in Veterinary Science, 2025 | 54 dogs | Treats with CBD alone or blended with L-tryptophan and α-casozepine before a 10-minute car trip, versus placebo | The authors described the effect as mild. Only one measure, a smaller cortisol rise with the blend, differed from placebo | Absorption varied widely between dogs. Short car trip, not a diagnosed anxiety condition |
What remains uncertain
Whether CBD helps dogs with clinical anxiety, such as separation anxiety, has not been established. Most trials used healthy dogs in short, staged situations rather than dogs with a diagnosed anxiety disorder followed over weeks. We do not know which products, if any, help, how long any effect lasts, or why individual dogs respond so differently. Effects on the liver and interactions with other medications are open questions that only your vet can weigh for your dog. And because extracts, carrier oils and amounts differ from one product to the next, a result from one study cannot be carried over to another product.
How to Evaluate a CBD Product for Dogs
No checklist can tell you whether a product will help. These criteria only help you screen out poorly documented products.
- A batch-specific certificate of analysis (COA). Look for an independent lab report that matches the batch number on your bottle and covers CBD content, THC and contaminants such as heavy metals and solvents.
- THC results. U.S. federal law uses a 0.3% delta-9 THC threshold to distinguish hemp from marijuana, but that legal threshold is not a veterinary safety threshold for dogs. Read the THC line on the COA and ask your vet whether any THC is acceptable for your dog.
- A formula made for dogs. Products made for people can contain ingredients that are unsafe for dogs, such as xylitol. Read the full ingredient list.
- A complete label. It should state the amount of CBD per serving or per chew, the full ingredients and a batch number.
- Modest wording. Be cautious with brands that promise to treat anxiety or replace medication. The FDA has acted against that kind of claim.
- Extract type. Full-spectrum extracts keep trace THC and other hemp compounds, broad-spectrum extracts are usually marketed as THC-free, and isolate is CBD alone. No type has been shown to work better for dog anxiety.
CBD Oils and Tinctures for Dogs
Products are grouped by format and then listed alphabetically by brand. The order is not a ranking. For each one, we separate what you can verify, what the brand says, what studies tested, and what remains uncertain.
cbdMD Broad Spectrum CBD Dog Oil Tincture
What you can verify: cbdMD lists this tincture as broad-spectrum and describes its pet products as THC-free, meaning below the level of detection by the methods it uses. The brand says batches are tested by third-party labs and links a COA and lab results page from its site.
What the brand says: The brand presents the product as part of its pet CBD line. Any wording about calming is marketing language, not a finding.
What studies tested: We did not find a published study of this product in dogs with anxiety.
What remains uncertain: Effects, long-term safety and interactions with other medications for this specific product.
ElleVet Sciences CBD+CBDA Oil
What you can verify: ElleVet sells oils, soft gels and chews for dogs. Its formulas combine CBD with CBDA, an acid form found in raw hemp, and the brand states that its products contain less than 0.3% THC. The site links a Certificate of Analysis page from its help section.
What the brand says: The brand describes its products as relaxation “without sedation” and refers on its site to a double-blind placebo study from Cornell University College of Veterinary Medicine. Its statements carry a standard notice that they have not been evaluated by the FDA.
What studies tested: ElleVet’s science page lists Cornell research on joint discomfort and on safety. For calming, the page lists a 2020 brand-hosted pilot study (white paper) of its calming chews in 24 dogs, in which the brand reports that 20 dogs showed fewer stress or anxiety-related behaviors. That pilot is not one of the peer-reviewed studies in the table above, and the page does not describe a control group. We did not find a peer-reviewed, placebo-controlled trial of ElleVet products for dog anxiety, so the Cornell study the brand mentions should not be read as proof for anxiety.
What remains uncertain: Whether any of this research applies to dogs with anxiety, and whether results would hold for other brands that use plain CBD.
Honest Paws Calm CBD Oil
What you can verify: Honest Paws describes its supplements as made with organic, full-spectrum hemp oil and states that its products contain less than 0.3% THC. The brand says every batch’s COA is available on its website.
What the brand says: The Calm line is marketed for calm and relaxation, with a notice that statements have not been evaluated by the FDA.
What studies tested: We did not find a published study of this product in dogs with anxiety.
What remains uncertain: Effects, and whether trace THC from a full-spectrum extract is acceptable for your dog. Ask your vet.
Medterra Pet CBD Tincture
What you can verify: Medterra describes its pet tincture as made with CBD isolate from non-GMO hemp in an MCT oil carrier, with no THC. The tincture is offered unflavored and in beef and chicken flavors. The brand says batch results from an accredited lab are available by scanning the QR code on the package.
What the brand says: Medterra markets its pet line for stress and a calm disposition, and states that its claims are not evaluated by the FDA.
What studies tested: We did not find a published study of this product in dogs with anxiety. Isolate and other extract types have not been compared in studies of dog anxiety.
What remains uncertain: Effects, and whether an isolate behaves differently from other extract types in dogs.
Penelope’s Bloom CBD Oil
What you can verify: Penelope’s Bloom sells pet tinctures, chews and treats, and its site links a Lab Reports page. Its disclaimer describes the hemp as organically farmed.
What the brand says: Several of its pet products are marketed for stress and anxiety. Treat that as marketing language, since the same site states that its products are not intended to treat any disease.
What studies tested: We did not find a published study of this product in dogs with anxiety.
What remains uncertain: Effects and consistency between batches.
CBD Chews for Dogs
Chews are easier to give than oil, but they may also contain other active ingredients, so read the full label and ask your vet about every ingredient.
cbdMD Broad Spectrum CBD Dog Calming Chews
What you can verify: cbdMD lists these chews as broad-spectrum and describes its pet products as THC-free, meaning below the level of detection by the methods it uses. It links a COA and lab results page from its site. Read the full ingredient list on the label before buying.
What the brand says: The chews are sold as a calming product. Treat that as marketing language, not a finding.
What studies tested: We did not find a published study of this product in dogs with anxiety. Studies of CBD alone do not tell us how a chew with other ingredients behaves.
What remains uncertain: Effects, and which ingredient in the chew, if any, causes any change.
Honest Paws Calm CBD Bites
What you can verify: Honest Paws says the Calm oil is also present in its bites and soft chews, and that every batch’s COA is available on its website. The brand states that its products contain less than 0.3% THC.
What the brand says: The chews are marketed for calm, with the standard FDA notice.
What studies tested: We did not find a published study of this product in dogs with anxiety.
What remains uncertain: Effects, and how the amount of CBD per chew compares with the amounts used in research.
Quick Comparison
This table compares documentation, not performance. It does not show which product works best, because that has not been tested.
| Product | Format | Extract type, per brand | Testing documents | Published research on this exact product |
|---|---|---|---|---|
| cbdMD Broad Spectrum CBD Dog Oil Tincture | Oil | Broad-spectrum, described as THC-free | COA page linked on site | No study found |
| ElleVet CBD+CBDA Oil | Oil, soft gel, chew | CBD with CBDA | COA page linked on site | Brand-hosted white paper on calming chews, separate from peer-reviewed studies |
| Honest Paws Calm CBD Oil | Oil | Full-spectrum | Batch COAs online | No study found |
| Medterra Pet CBD Tincture | Oil | Isolate | Batch results by QR code on package | No study found |
| Penelope’s Bloom CBD Oil | Oil | See product page | Lab Reports page linked on site | No study found |
| cbdMD Broad Spectrum CBD Dog Calming Chews | Chew | Broad-spectrum, described as THC-free | COA page linked on site | No study found |
| Honest Paws Calm CBD Bites | Chew | Calm oil, described as full-spectrum | Batch COAs online | No study found |
Hemp Oil on Amazon: Not the Same as the CBD Products Above
Amazon’s policies do not allow the sale of CBD products, so the CBD products reviewed above are sold through their own brand sites. What Amazon lists for pets are hemp seed oil and hemp extract products. These are not equivalent to the CBD products reviewed above, and none of the studies in this article tested them.
We include two of them only because readers ask what they will find on Amazon. They are not treatments for anxiety, and we do not recommend them for that purpose. Amazon listing titles often make health promises. We do not repeat those promises here, and the FDA has not evaluated them. Read the ingredient panel and ask your vet before giving any supplement.
| Product | Brand | What the listing describes | Link |
|---|---|---|---|
| Hemp Oil for Dogs and Cats | Billion Pets | Hemp oil drops sold for dogs and cats | View on Amazon |
| Max Potency Hemp Oil, 2 pack | HMone | Hemp oil sold for dogs and cats | View on Amazon |
Check the current Amazon listing for price, availability and customer ratings. As an Amazon Associate, we earn from qualifying purchases.
Questions to Ask Your Vet Before Trying CBD
Bring the product label and COA to your appointment. These questions can help you decide together whether CBD is worth discussing at all:

- Could a medical problem, such as pain, be contributing to my dog’s anxiety or behavior changes?
- Are there established options, such as behavior modification or prescription medication, that I should consider first or alongside?
- Is CBD appropriate for my dog’s age, health and current medications, including how it might affect the liver?
- Is any amount of THC acceptable for my dog?
- Which product, if any, would you be comfortable with, and how would we judge whether it is helping or causing problems?
- What signs should make me stop and call you?
CBD should never replace veterinary care, and you should not start, stop or combine it with other medications without your vet’s guidance.
Common Mistakes to Avoid
- Treating CBD as a substitute for a vet visit. Anxiety can come from pain, illness or a life change, and it is not always a behavior problem.
- Judging a product by the label alone. Phrases such as “vet-formulated,” “premium” or “organic” are not proof. Look for a batch-specific COA from an independent lab.
- Using a product made for people. It may contain ingredients that are unsafe for dogs, such as xylitol, essential oils or alcohol.
- Treating the legal THC limit as a safety limit. The 0.3% threshold defines hemp in federal law. It does not tell you whether a product is suitable for your dog.
- Assuming one study covers every product. A study of one extract does not show that another extract works the same way.
- Combining products without guidance. Calming chews can contain other active ingredients, and CBD may interact with other medications. Tell your vet about everything your dog takes.
- Skipping training and environment. Behavior plans, exercise and a predictable routine are the foundation of most anxiety care. A supplement is not a plan.
- Ignoring warning signs. Contact your vet if your dog seems unwell, unusually sleepy, uncoordinated or stops eating.

Frequently Asked Questions
Is CBD approved by the FDA for dogs?
No. The FDA has not approved any CBD product for use in animals. Statements on pet CBD labels and websites have not been evaluated by the agency. Check the FDA’s current guidance on cannabis and animal health, and talk to your vet.
Does CBD work for dog anxiety?
The evidence is limited and mixed. Small studies of healthy dogs in short, staged situations have reported results that range from no effect to mild or measure-specific effects, and each tested a single product. Whether CBD helps dogs with diagnosed anxiety has not been established.
Is CBD safe for dogs?
Safety depends on the product, the dog and the situation, and it has not been established for pet CBD products as a group. Quality varies, products can contain THC or unsuitable ingredients, and CBD may interact with other medications or affect the liver. Your vet is the right person to judge the risks for your dog.
Should I give my dog CBD instead of medication?
No. Do not stop or replace a prescribed medication with CBD. If your dog takes medication or has a health condition, ask your vet before adding any supplement.
Is full-spectrum, broad-spectrum or isolate CBD better for dogs?
No type has been shown to work better for dog anxiety. The types differ in what they contain, mainly in whether trace THC or other hemp compounds are present. Choose based on the COA, the label and your vet’s advice.
Key Takeaways
- The FDA has not approved any CBD product for animals.
- Studies on CBD and canine stress are small, short and mixed, and each tested one product, so results do not transfer to other products.
- A brand’s description of its own product is marketing, not evidence.
- The legal 0.3% THC threshold for hemp is not a veterinary safety threshold for dogs.
- Look for a batch-specific COA from an independent lab, a complete label and modest wording.
- Amazon hemp oil is not the same as the CBD products reviewed here and is not a treatment for anxiety.
- Start with your vet. CBD should never replace veterinary care, training or prescribed medication.
Sources
- FDA. FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD), section on pets and other animals (content current as of July 16, 2024). Main FDA source. fda.gov
- FDA, Center for Veterinary Medicine. FDA Warns Four Companies for Illegally Selling CBD Products Intended for Use in Food-Producing Animals (content current as of May 26, 2022). Additional source. fda.gov
- FDA. What You Need to Know (And What We’re Working to Find Out) About Products Containing Cannabis or Cannabis-derived Compounds, Including CBD (content current as of March 5, 2020). Additional source. fda.gov
- Morris EM et al. The Impact of Feeding Cannabidiol (CBD) Containing Treats on Canine Response to a Noise-Induced Fear Response Test. Frontiers in Veterinary Science, 2020. frontiersin.org
- Hunt ABG, Flint HE, Logan DW, King T. A single dose of cannabidiol (CBD) positively influences measures of stress in dogs during separation and car travel. Frontiers in Veterinary Science, 2023. frontiersin.org
- Flint HE, Weller JE, Hunt ABG, King T. Treats containing cannabidiol, L-tryptophan and α-casozepine have a mild stress-reducing effect in dogs. Frontiers in Veterinary Science, 2025. frontiersin.org
- ElleVet Sciences. Science and research page, brand-published list of studies. ellevetsciences.com/science
- Brand websites used for product details: cbdMD, ElleVet Sciences, Honest Paws, Medterra, Penelope’s Bloom

